: Download and install iTunes 11.1.5 (32-bit or 64-bit depending on your OS). This specific version is widely cited as the most stable for running p0sixspwn.
on your computer
: Turn off your device's passcode and find my iPhone/iPad features before starting. p0sixspwn requires itunes 105 or above
If you are trying to jailbreak a device that is not fully compatible (e.g., trying to use it on an iPhone 5), the tool will fail. P0sixspwn is primarily for devices that run iOS 6 natively, such as the iPhone 4, iPhone 3GS, and iPod Touch 4th Gen.
: Connect your device and launch p0sixspwn. It should now correctly detect your device and the iTunes environment. Troubleshooting Continued Failures : Download and install iTunes 11
After downgrading to iTunes 11.1.5 as described above, locate the p0sixspwn-1.0.8.exe file.
This is the fix. You need to uninstall your current iTunes and install a legacy version that p0sixspwn recognizes. If you are trying to jailbreak a device
The structure of this critical connection component was completely redesigned.
If you are a veteran in the iOS jailbreaking community, the name brings back memories of the iOS 6.1.3–6.1.6 untethered jailbreak era. Developed by the infamous evad3rs team (winocm, posixninja, and others), p0sixspwn was a savior for users stuck on older devices like the iPhone 3GS, iPhone 4, and iPod touch 4th generation.
You do not necessarily need to downgrade all the way to iTunes 10. Apple released a specific version of iTunes 12.1.1 for 64-bit Windows systems that retains older, 32-bit video card and device driver compatibility. This version fixes the p0sixspwn error instantly.